Bhimanagouda Patil

Teaching Focus

My teaching focusses on linking and food and health.  Developed three unique and multidisciplinary courses,

1) Science of foods for health;

2) The nexus of food & nutritional security, hunger and sustainability;

3) Phytochemicals in fruits and vegetables to improve human health.

Courses emphasize the connections between fruits, vegetables, food and their health-promoting properties and provide information based on evolving science.

Area of Expertise: 

Food for health and isolation and characterization of bioactives

Staff and student support

Adhikari,Jayashan , Majithia,Drishti, and Ravindranath,Varsha

Research Focus

Research focusses on ‘Foods for Health’ through farm-to-table approaches include examining pre- and postharvest effects on bioactive compounds, isolating and characterizing these compounds from different fruits and vegetables, as well as understanding their roles in human health. Specific projects involve 1) development of a novel green (i.e. limiting the use of toxic chemicals) technology for isolation and purification novel bioactive compounds2) using mechanistic studies of cellular and animal models to provide proof of concept that bioactives reduce risk from prostate, breast, pancreatic, and colon cancer; 3) showing that a structural motif in nomilin from citrus fruits is essential for its inhibition of a cancer-promoting factor; 4) finding that citrus flavonoids and limonoids suppress bacterial cell-cell signaling, biofilm formation, and type III secretion; 5) development of a green nanoparticle synthesis method and showing that these nanoparticles enhanced onion quality.  His close working relationship with the produce industry is a model for faculty in a land grant university, and the Texas produce industry has targeted plenty of their marketing efforts around the “foods for health” banner.

Select Publications

1. Acharya, P., Jayaprakasha, G.K., K.C. Crosby., J.L. Jifon, S. Patil. (2020). Nanoparticle-Mediated Seed Priming Improves Germination, Growth, Yield, and Quality of Watermelons (Citrullus lanatus) at multilocations in Texas. Scientific Reports (Nature Publisher Group)10:1-16.
2. Knobloch, N. A., Charoenmuang, M., Cooperstone, J.L., and Patil, B.S. “Developing Interdisciplinary Thinking in a Food and Nutritional Security, Hunger, and Sustainability Graduate Course.” The Journal of Agricultural Education and Extension, 1–15.
3. Acharya, P., Jayaprakasha, G.K., K.C. Crosby., J.L. Jifon, S. Patil. (2020). 1H Nuclear Magnetic Resonance and Liquid Chromatography Coupled with Mass Spectrometry-Based Metabolomics Reveal Enhancement of Growth-Promoting Metabolites in Onion Seedlings Treated with Green-Synthesized Nanomaterials. Journal of Agricultural and Food Chemistry, 2020.
4. Kasote, D. GK Jayaprakasha and Patil, B.S. (2019). Leaf Disc Assays for Rapid Measurement of Antioxidant Activity. Scientific Reports 1884:1-10.
5. Singh, J. GK Jayaprakasha and Patil, B.S. (2018). An optimized solvent extraction and rapid identification of unidentified flavonoid glucuronide derivatives from spinach by UHPLC-HR-QTOF-MS. Talanta. 188:763-771.
6. Murthy, K.N.C., Jayaprakasha, G. K., S. Patil. (2012) D-limonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells. Life Sciences, 91: 429-439. PMID: 22935404
7. Kim, J., Jayaprakasha, G.K., Muthuchamy, M., and S. Patil. (2011) Structure-function relationships of citrus limonoids on p38 MAP kinase activity in human aortic smooth muscle cells. European Journal of Pharmacology, 670: 44-48. PMID: 21924259
8. Patil, B.S. Jayaprakasha, G.K., Murthy, K.N.C., and A. Vikram. (2009) Bioactive compounds: historical perspectives, opportunities, and challenges. Journal of Agriculture and Food Chemistry, 57: 8142-8160. PMID: 19719126.
9. Miller, E.G., Peacock, J.J., Campbell, T., Bourland, S.E., Taylor, J.M. Wright, J.M. and S. Patil. (2008) Inhibition of oral carcinogenesis by citrus flavonoids. Nutrition and Cancer, 60: 69-74. PMID: 18444138.
10. Yu, J., Wang, L., Walzem, R.W., Miller, E.G., Pike, L.M., and S. Patil. (2005) Antioxidant activity of citrus limonoids, flavonoids and coumarins. Journal of Agriculture and Food Chemistry, 53:2009-2014. PMID: 15769128.